A Prospective, Randomized Clinical Study on the Effects of Casein Phosphopeptide-amorphous Calcium Phosphate (CPP-ACP) Paste on Plaque, Gingivitis and White Spot Lesions in Orthodontic Patients - Part 2

A Prospective, Randomized Clinical Study on the Effects of CPP-ACP Paste on Plaque, Gingivitis and White Spot Lesions in Orthodontic Patients - Part 2

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00670618

Enrollment

325

Registered

2008-05-02

Start date

2008-10-01

Completion date

2011-04-26

Last updated

2023-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early Caries Lesions

Brief summary

Influence of CPP-ACP paste and Elmex Medical Gel on the prevention of white spot lesions in orthodontic patients during fixed appliances.

Interventions

DEVICECPP-ACP (GC Tooth Mousse)

Calcium and phosphate

DEVICECPP-ACP (GC MI Paste Plus)

Calcium, phosphate and fluoride

DEVICEFluoride (Elmex Medical Gel)

Fluoride

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

10 Years to 60 Years

Healthy volunteers

Inclusion criteria

* No white spot lesion at the time of placement of fixed appliances

Exclusion criteria

* White spots already present before start orthodontic treatment

Design outcomes

Primary

Measure	Time frame
Prevention of the opacity of white spots during orthodontic treatment with fixed appliances	After 2 years

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026