Supplemental Perioperative Oxygen to Reduce the Incidence of Post-Cesarean Endometritis and Wound Infection

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00670020

Enrollment

143

Registered

2008-05-01

Start date

2001-01-31

Completion date

2006-12-31

Last updated

2008-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wound Infection or Endometritis Post Cesarean Section

Keywords

Women undergoing Cesarean section after the onset of labor

Brief summary

The purpose of this study is to determine whether supplemental perioperative oxygen significantly decreases the incidence of post-Cesarean endometritis and wound infection among women who undergo Cesarean section after the onset of labor.

Detailed description

Women undergoing cesarean section after rupture of membranes or onset of labor are randomized in a one to one ratio to either normal or supplemental perioperative oxygen during cesarean section and for two hours afterwards.

Interventions

PROCEDUREsupplemental perioperative oxygen

increased perioperative oxygen verses non-interventional oxygen

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

FEMALE

Age

16 Years to No maximum

Healthy volunteers

Inclusion criteria

* Women who underwent a clinically indicated cesarean delivery after the onset of labor or rupture of membranes

Exclusion criteria

* Cesarean delivery prior to the onset of labor or rupture of membranes * emergent cesarean delivery * general endotracheal anesthesia * clinical chorioamnionitis * HIV infection * less than 16 years of age

Design outcomes

Primary

Measure	Time frame
surgical site infection	within two weeks of cesarean section

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026