Neuropathic Pain Database

National Neuropathic Pain Database Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00669006

Acronym

NePDatabase

Enrollment

789

Registered

2008-04-29

Start date

2008-04-30

Completion date

2020-02-24

Last updated

2021-10-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuropathic Pain

Keywords

neuropathic pain, database, prospective, national

Brief summary

To establish the infrastructure for a national neuropathic pain database. To determine the longterm outcome of the management of chronic neuropathic pain including pain relief, disability, and quality of life.

Detailed description

The database will provide standard information on demographics, diagnosis, treatment interventions and outcome modeled on guidelines from the expert panel on initiatives on Methods, Measurement and Pain Assessment in Clinical Trials (IMMPACT)(Turk et al.,Pain 2003;106:337-345) The IMMPACT panel determined that patients should be evaluated according to six core domains as follows: Pain, physical functioning, emotional functioning, subject rating of global satisfaction with treatment, symptoms and adverse events and subject disposition. The database will allow us to examine outcomes based on single (eg. pregabalin) and multiple (e.g tricyclic antidepressants and gabalin) therapeutic interventions. Standard guidelines for management of neuropathic pain acknowledge that polypharmacy is appropriate when individual first line treatments fail to provide adequate pain relief (Gilron I et al., CMAJ 2006; 175: 265-275; Attal N et al., European Journal of Neurology 2006; 13: 1153-1169)

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Primarily Neuropathic Pain * Able to give informed consent * Estimated Life Expectancy of 2 years

Exclusion criteria

* Not primarily neuropathic pain * Declined participation- too much traveling * Declined participation- Unknown * Declined participation- Other, specify * Considered unreliable- personality disorder * Considered unreliable- cognitive impairment * Considered unreliable- substance abuse * Considered unreliable- Other * Language barrier * Exceeded quarterly quota * Presentation with progressive or recurrent cancer, fibromyalgia, perineal pain of unknown etiology * Other, specify

Design outcomes

Primary

Measure	Time frame	Description
To establish the infrastructure for a national Neuropathic Pain Database.	2 years	To establish the infrastructure for a National Neuropathic Pain Database, with a composite primary outcome measure in average pain intensity (based on average pain intensity of BPI) and reduction in disability (based on Interference Scale Score of BPI))

Secondary

Measure	Time frame
To determine the longterm outcome of the management of chronic neuropathic pain including pain relief, disability and quality of life.	2 years

Countries

Canada

Outcome results