Cytomegalovirus (CMV) Transmission by Frozen Breast Milk in Preterms

Incidence and Clinical Outcome of Human Cytomegalovirus Transmission Via Thawed Frozen Breast Milk in Preterm Infants <31 Weeks. A Prospective Trial.

Status

Suspended

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00668798

Enrollment

Registered

2008-04-29

Start date

2005-01-31

Completion date

2008-03-31

Last updated

2008-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cytomegalovirus

Keywords

cytomegalovirus breast milk preterm infants transmission, transmission of CMV via thawed frozen breast milk

Brief summary

Cytomegalovirus infection threatens preterm infant. We investigated, whether thawed breast milk is a mode of transmission

Detailed description

Preterm infants are at risk of symptomatic human cytomegalovirus infections transmitted by breast milk. This study evaluates incidence, timing, and clinical rlevance of acquired human CMV infections in preterm infants younger than 32 weeks of gestational age receiving maternal thawed frozen breast milk until 33 completed weeks of gestational age.

Interventions

None listed

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

24 Weeks to 31 Weeks

Healthy volunteers

Inclusion criteria

* preterm infants of less than 32 weeks of gestation

Exclusion criteria

* preterm infant of 32 weeks of gestational age or older, feeding with solely formula milk * ourborn infants * retroviral infection * CMV status of mother unclear * informed consent missing

Design outcomes

Primary

Measure	Time frame
CMV status of preterm infants	2005-2008

Secondary

Measure	Time frame
clinical manifestations of CMV infection	2005-2008

Countries

Germany

Outcome results