Lung Cancer
Conditions
Brief summary
The purpose of this study is to determine whether the use of platelet-rich plasma (PRP) and concentrated platelet-poor plasma (PPPc) can reduce the duration of post-operative air leak after lobectomy for lung tumours.
Interventions
PROCEDUREStandard post-lobectomy wound care plus use of PRP and PPPc prepared by GPS and Plasmax respectively
GPS is used to create the platelet rich plasma (PRP). Plasmax is used to create the concentrated platelet-poor plasma (PPPc). Both PRP and PPPc will be used for wound care in the thoracic cavity post-lobectomy.
PROCEDUREStandard post-lobectomy wound care
Standard post-lobectomy wound care
Sponsors
University of Western Ontario, Canada
Zimmer Biomet
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients requiring a lobectomy
Exclusion criteria
* Pneumonectomy * Sleeve lobectomy * Determination of unresectability (prior to the initiation of lobectomy) * Wedge resection alone
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of postoperative air leak | Every 4 hours of postop hospital stay, between 4-6 weeks postop |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of air leak, Prolonged air leak (> days), Complications | Every 4 hours of postop hospital stay, between 4-6 weeks postop |
Countries
Canada
Outcome results
None listed