Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy

Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy Using Multidetector Computed Tomography Scan and Color Doppler Imaging.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00665795

Enrollment

Registered

2008-04-24

Start date

2005-07-31

Completion date

2013-11-30

Last updated

2013-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dysthyroid Orbitopathy

Keywords

Dysthyroid Optic Neuropathy, multidetector computed tomography, color doppler, Grave´s Orbitopathy, Grave´s Disease, morphometric analysis

Brief summary

The purpose of this protocol is to study orbital structures in Graves´ Disease using multidetector computed tomography and color doppler imaging. Some changes in orbital structures detected by imaging exams could predict severity of the ocular Graves´disease. Thus the study could be useful in improve medical management of patients with Graves´ Disease.

Detailed description

Morphometric analysis of orbital structures in Graves´ Orbitopathy using multidetector computed tomography scan and color doppler imaging: Patients with Graves´ orbitopathy are evaluated by a complete ophthalmic examination.A prospective study with Multidetector CT scan and Color Doppler of these patients are made to develop parameters capable to predict Dysthyroid Optic Neuropathy (DON).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* Graves´Orbitopathy diagnosed based on previously reported criteria * Age above 20 years * Good cooperation for performing Visual Field test * Spherical refraction within ± 5 D and cylinder correction within ± 3 D

Exclusion criteria

* Graves´Orbitopathy not diagnosed

Design outcomes

Primary

Measure	Time frame
screening indexes for dysthyroid optic neuropathy	indexes above 60% of orbital apex crowding were high suspected for DON

Countries

Brazil

Outcome results