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Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome

Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00664300
Enrollment
60
Registered
2008-04-22
Start date
2007-08-31
Completion date
2009-10-31
Last updated
2011-01-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gilles de la Tourette's Syndrome

Keywords

Gilles de la Tourette's syndrome, Facial expression recognition of emotion, Frequency levels, Automatic and voluntary information treatment, Patient with Gilles de la Tourette's syndrome

Brief summary

Gilles de la Tourette's syndrome is a childhood onset inherited neuropsychiatric disorder characterised by the presence of both multiple motor tics and one or more vocal tics (noises), with psychiatric and/or behaviour disorders (such as obsessive compulsive behaviour…). This disease is associated with an dopamine system imbalance which could be responsible of a specific trouble in the recognition in some facial expression. This has been already shown in Gilles de la Tourette patients with obsessive compulsive behaviour. We hypothesise that patients with Gilles de la Tourette's syndrome present a dysfunction of voluntary and automatic treatment of emotional information. The main purpose of this study is to show if patients with Gilles de la Tourette's syndrome present a lack of specific facial expression recognition of emotion and determinate more precisely if this alteration involves the cortical way (high frequency way) or the under cortical way (low frequency way).

Detailed description

20 patients with Gilles de la Tourette's syndrome compared to 20 healthy paired volunteers. Study progress (patients): Inclusion visit : Psychiatric evaluation Psychological evaluation Ophthalmic visit Protocol : Facial expression recognition test Lexical decision test Study progress (healthy volunteers): Psychiatric evaluation Ophthalmic visit Facial expression recognition test Lexical decision test

Interventions

Facial expression recognition test Lexical decision test

Sponsors

University Hospital, Clermont-Ferrand
Lead SponsorOTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Age : \>18 years * Patient with a Gilles de la Tourette 's syndrome such as defined in the DSMIV * Stability of treatment \>1 month * Mini Mental State \> 26 * Affiliation to social security * Agreement of patients

Exclusion criteria

* Patients with cognitive disorders, dementia, mental retardation… * Patients with serious neurological pathologies * Patients with a vision contrast altered. * Patients who do not understand the words associated with an emotion * Pregnant women * Person who participate to an other study

Design outcomes

Primary

MeasureTime frame
Facial expression recognition test% of exact responses

Secondary

MeasureTime frame
Lexical decision testThe time to respond

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026