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A Comparison of Two Exercise Programs on Knee Motor Control

The Effect of Specific Versus Generalised Quadriceps Exercise on Neural Control of the Vasti

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00662493
Enrollment
60
Registered
2008-04-21
Start date
2003-03-31
Completion date
2005-12-31
Last updated
2008-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Pain, Patellofemoral Pain

Keywords

knee pain, exercise, rehabilitation

Brief summary

Pain at the front of the knee is a common condition treated by physical therapists. Treatment may consist of generalised strengthening exercises directed at the quadriceps muscle or specific retraining aimed at restoring motor control at the knee. This study compared these two exercise programs in a group of people who were painfree at the time to evaluate their effect on motor control. It was hypothesised that only the motor retraining program would influence motor control at the knee.

Interventions

BEHAVIORALMotor control retraining program

Specific retraining of VMO activation in a low-load situation,and progressed to integrate more functional positions. Use of dual channel biofeedback was incorporated

BEHAVIORALQuadriceps strengthening program

4 exercises focused on quadriceps strengthening commencing at a resistance of 60% 1 repetition maximum. Each exercise was performed for 3 sets of 10 repetitions

Sponsors

National Health and Medical Research Council, Australia
CollaboratorOTHER
University of Melbourne
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
16 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* aged between 16-40 years, with the upper age limit to reduce the likelihood of osteoarthritic changes in the patellofemoral joint * a self-reported history of anterior or retropatellar knee pain with insidious onset of symptoms and with at least one episode of pain in the past 12 months where pain was aggravated by at least two of the following: prolonged sitting, stairs, squat, running, kneeling and hopping/jumping * currently asymptomatic for at least 8 weeks prior to assessment * delay in the onset of VMO EMG relative to that of VL of greater than 10 ms during either the ascent or descent of a stair stepping task

Exclusion criteria

* current knee pain * history of knee surgery or other knee injury in previous 12 months * physiotherapy treatment for knee pain in the past 12 months * history of patellar dislocation/subluxation * clinical evidence of meniscal lesion, ligamentous instability, traction apophysitis around the patellofemoral complex, patellar tendon pathology, chondral damage, osteoarthritis and spinal referred pain * current lower limb pathology affecting their ability to satisfactorily complete the testing or exercise protocol * current use of non-steroidal anti-inflammatory or corticosteroid drugs * inability to communicate and comprehend written or verbal instructions in English

Design outcomes

Primary

MeasureTime frame
latency between the onset of VMO electromyographic activity relative to that of VL during stair ascent and stair descent measured using surface electrodes6 weeks with 8 week followup

Secondary

MeasureTime frame
Concentric and eccentric quadriceps muscle strength as assessed by isokinetic dynamometry6 weeks with 8 week followup

Countries

Australia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026