Comparison of Point of Care to Lab INR in Dialysis Patients on Warfarin

Correlation of Point of Care INR to Laboratory INR in Hemodialysis Patients Taking Warfarin

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00660946

Enrollment

Registered

2008-04-17

Start date

2005-06-30

Completion date

2005-12-31

Last updated

2023-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anticoagulation in Dialysis Patients

Keywords

anticoagulation in dialysis patients, chronic anticoagulation, warfarin, hemodialysis, INR, Point of Care

Brief summary

To determine whether point of care (POC) International Normalized Ratio (INR) test results correlate with plasma INR measures in hemodialysis patients.

Detailed description

37 chronic hemodialysis patients being anticoagulated with warfarin require INR monitoring routinely.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to No maximum

Healthy volunteers

Inclusion criteria

* Chronic dialysis patients on chronic warfarin anticoagulation.

Exclusion criteria

* On warfarin for less than 1 month.

Design outcomes

Primary

Measure	Time frame
To determine whether Point of Care INR testing would be suitable in the management of dialysis patients on chronic warfarin therapy	Not an intervention study, but observational in this cohort

Secondary

Measure	Time frame
Determine whether Point of Care INR devices maintain test accuracy in dialysis patients who are temporarily anemic (HCT <32%) according to their CBC	Not an intervention study, but observational in the cohort (statistics completed 1.5 yrs)

Outcome results