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Treatment Effects of Narrative Exposure Therapy

Treatment Effects of Narrative Exposure Therapy on Psychiatric Symptoms and Cortisol Levels in Patients With Posttraumatic Stress Disorder

Status
UNKNOWN
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00660439
Enrollment
40
Registered
2008-04-17
Start date
2007-05-31
Completion date
2010-11-30
Last updated
2008-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Posttraumatic Stress Disorder

Keywords

PTSD

Brief summary

This study compares Narrative Exposure Therapy with a Waiting list control group, both consists of traumatized patients with diagnosed Posttraumatic Stress Disorder. The main aim is to investigate if the patients psychiatric symptoms and levels of the stress hormone cortisol will improve more after Narrative Exposure Therapy than the Waiting list (i.e. no intervention).

Detailed description

In this study we want to compare Narrative Exposure Therapy (NET) to Waiting list controls. Adult patients with diagnosed Posttraumatic Stress Disorder following different types of trauma, will be included. Clinicians in psychiatric outpatient clinics will treat patients with NET, either immediately after assessment, or after a second assessment 3 months later. All patients will also be assessed 1 and 6 months after treatment completion. All patients will be assessed for psychiatric symptoms by the Mini International Neuropsychiatric Interview (version 5.0.0) and the Clinician-Administered PTSD Scale. Patients will also answer several questionnaires (IES-R, SCL-90, BDI-II, DES and UCL). Baseline level of the stress hormone cortisol will be collected in saliva for measuring the diurnal cycle. We will investigate if patients with Posttraumatic Stress Disorder will show more symptom improvement with NET than those on the waiting list (i.e. no intervention) in addition to measuring potential differences in cortisol between the groups.

Interventions

BEHAVIORALNarrative Exposure Therapy

Psychological treatment, with narration of positive and traumatic events in patients history, including in vivo exposure of traumatic events. The narrative is written down by the therapist.

Sponsors

Norwegian Center for Violence and Traumatic Stress Studies
CollaboratorOTHER
University of Bergen
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Posttraumatic Stress Disorder (PTSD) * Age above 18 years * Understands, speaks and writes Norwegian * Informed, written consent

Exclusion criteria

* Active psychosis * Active suicidality * Serious self mutilation * Active alcohol or drug abuse * Serious dissociative symptoms * Disease in nervous system or head injury * Hormonal disease * Pregnancy

Design outcomes

Primary

MeasureTime frame
Psychiatric symptoms1 and 6 months after treatment

Secondary

MeasureTime frame
Cortisol in saliva1 and 6 months after treatment

Countries

Norway

Contacts

Primary ContactTove S. Nordling, Cand Psychol
tsno@helse-bergen.no+47 55976691

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026