Myeloid-Related Protein in Evaluation of Acute Chest Pain in the Emergency Departement

Study of Myeloid-related Protein 8/14 and Additional Biomarkers (Multi Marker Approach) for Early Diagnosis and Risk Stratification in Patients Presenting With Acute Chest Pain at the Emergency Department

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00657436

Acronym

MyRiAD

Enrollment

403

Registered

2008-04-14

Start date

2008-03-31

Completion date

2010-12-31

Last updated

2012-05-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Coronary Syndrome, Coronary Occlusion, Coronary Thrombosis, Myocardial Infarction, Myocardial Ischemia

Keywords

Acute Coronary Syndrome, Myocardial Infarction, Coronary Artery Disease

Brief summary

The purpose of the study is the evaluation of multiple biomarkers related to acute coronary syndromes, including myeloid-related protein 8/14 (MRP 8/14), along with established clinical markers, for early diagnosis and risk stratification in patients presenting with acute chest pain at the emergency department. Study hypothesis: MRP 8/14, alone or together with other established or new biomarkers, increases the earliness, sensitivity, and specificity of diagnosing acute coronary syndromes.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* All patients in the emergency department of the University Hospital Zurich with measurement of troponin during the routine diagnostic evaluation.

Exclusion criteria

* Refusal or inability to give informed consent.

Design outcomes

Primary

Measure	Time frame
Diagnosis of acute coronary syndrome	Emergency room and/or hospital stay

Secondary

Measure	Time frame
Incidence of any acute coronary event	1 year
Morbidity from coronary artery disease	1 year
Mortality	1 year

Countries

Switzerland

Outcome results