The Pleiotropic Effects of Atorvastatin When Combined With Common Antihypertenisve Medications.

The Pleiotropic Effects of Atorvastatin When Combined With Common Antihypertenisve Medications: A Comparison of Amlodipine and Hydrochlorothiazide

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00656331

Enrollment

Registered

2008-04-11

Start date

2005-08-31

Completion date

2012-06-30

Last updated

2023-07-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Brief summary

The purpose of this study is to compare the effects of the cholesterol medication taken with each blood pressure medication alone on heart disease risk factors including blood pressure, cholesterol, inflammation, blood sugar control, blood vessal function, and other heart disease risk factors.

Interventions

DRUGAmlodipine and Hydrocholorothiazide

Arm 1 gets Amlodipine and Arm 2 gets Hydrocholorothiazide

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* mild hypertension and high cholesterol

Exclusion criteria

* diabetes and heart disease

Design outcomes

Primary

Measure	Time frame
PAI-1	study completion

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026