Hydrocephalus
Conditions
Keywords
Hydrocephalus, shunt dysfunction, shunt flow
Brief summary
The study hypothesis is that a transit-time ultrasonic sensor can help doctors diagnose a malfunctioning shunt valve. The study will simulate an implanted shunt flow monitoring system by placing the flow sensor and a programmable shunt valve into the patient's Extra-Ventricular Drainage line. Flow will be measured as the doctor raises/lowers the drainage bag to simulate the patient sitting up/lying down. The doctor will simulate a malfunctioning shunt by changing the valve's pressure release settings for each cycle of raising/lowering the bag. By monitoring shunt flow during these changes, the doctors hope to develop new ways to diagnose malfunctioning shunt valves when implanted shunt flow monitors become available.
Interventions
None listed
Sponsors
National Institute of Neurological Disorders and Stroke (NINDS)
Transonic Systems Inc.
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
No minimum to 20 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosed with Hydrocephalus * Newborn through age 20 * External Ventriculostomy with an Extra-Ventricular Drainage system installed
Exclusion criteria
* Not diagnosed with Hydrocephalus * Older than age 20 * No External Ventriculostomy with an Extra-Ventricular Drainage system installed
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Volumetric flow of patient cerebrospinal fluid through an Extra-Ventricular Drainage System as a function of the shunt valve pressure release setting and drainage bag position. | 24 to 48 hours |
Secondary
| Measure | Time frame |
|---|---|
| Recording of the pressure waveform related to the volumetric flow of patient cerebrospinal fluid through an Extra-Ventricular Drainage system. | 24 to 48 hours |
Countries
United States
Outcome results
None listed