Skip to content

Use of Multiphoton Microscopy in the Diagnosis of Cancer

Use of Multiphoton Microscopy in the Diagnosis of Cancer

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00652210
Acronym
MPM
Enrollment
344
Registered
2008-04-03
Start date
2005-06-30
Completion date
2015-09-30
Last updated
2015-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder Cancer, Prostate Cancer

Keywords

Bladder cancer, prostate cancer, multiphoton microscopy

Brief summary

Multiphoton microscopy (MPM) has been shown to be able to image tissue at a cellular level. Our project will initially evaluated the ability of MPM imaging to distinguish normal bladder urothelium from atypical and malignant urothelium in the ex vivo setting. After development of sufficient criteria, we plan to develop an endoscopic bladder probe that will provide a non-invasive means to image the interior of the bladder at the cellular level, which would provide direct evidence of the presence of tumor without a biopsy. After exhibiting usefulness of MPM imaging for bladder cancer, we will look at other organs beginning with the colon.

Detailed description

Same as above

Interventions

OTHERMultiphoton microscopy

Use of multiphoton microscopy to diagnose cancer

Sponsors

Weill Medical College of Cornell University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
21 Years to 85 Years
Healthy volunteers
Yes

Inclusion criteria

* Anyone who presents with bladder and/or prostate cancer

Design outcomes

Primary

MeasureTime frame
After several delays, the multiphoton microscope has been delivered to Weill Cornell Medical College. We have been using this time to set-up and fine tune the multiphoton microscope. As of current, no negative events have occurred.10/14/2007 to 2/15/2008

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026