Cardiac Arrest
Conditions
Keywords
CPR, Preshock CPR, OHCA, EMS
Brief summary
1. Pre-shock cardiopulmonary resuscitation might benefit the survival of out-of-hospital cardiac patients with ventricular fibrillation / ventricular tachycardia in a post-hoc analysis of a prehospital trial conducted in Europe (L.Wik,2002). However, it's effectiveness in the Asian countries, where most firstly recorded rhythm in out-of-hospital cardiac arrests patients were asystole/pulseless electric activity rather than ventricular fibrillation / ventricular tachycardia, were not explored yet. 2. This trial was designed to exam if pre-shock cardiopulmonary resuscitation by emergency medical technicians improves the outcome of all out-of-hospital cardiac arrest patients in an Asian metropolitan city.
Detailed description
1. Different from data from the Western countries, non-shockable rhythm (Asystole/pulseless electric activity) was responsible for most out-of-hospital cardiac arrest patients(80%\ 90%) in metropolitan Taipei. 2. Response time in Taipei emergency medical service was longer than 5 minutes. 3. Bystander cardiopulmonary resuscitation rate were relatively low in Taipei. 4. Cardiopulmonary resuscitation is the only known method to save out-of-hospital cardiac arrest patients with asystole/pulseless electric activity. For those suffered from ventricular fibrillation/ ventricular tachycardia,previous studies revealed pre-shock cardiopulmonary resuscitation may have the potential to improve the outcome. 5. Study hypothesis: Compared with current standard resuscitative sequence (basic life support protocol in Guideline 2005), longer pre-shock cardiopulmonary resuscitation provided to all out-of-hospital cardiac arrest patients in Taipei may improve the outcome of them.
Interventions
10 cycles of 30:2 cardiopulmonary resuscitation before rhythm analysis by AED
Rhythm analysis as soon as AED is ready
Sponsors
Study design
Eligibility
Inclusion criteria
* Patients with out-of-hospital cardiac arrest
Exclusion criteria
* Trauma * Age \< 18y/o * Airway obstruction * Submersion * Sign of obvious death * existing do not resuscitate (DNAR) order * family refusal * preceding CPR by BLS teams for longer than 2 minutes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sustained ROSC >= 2 hours | 180 days |
Secondary
| Measure | Time frame |
|---|---|
| surival to ICU admission | 180 days |
| survival to hospital discharge | 180 days |
| Rates of good neurology recovery (CPC 1 &2) | 180 days |
Countries
Taiwan