Fibromyalgia, Hormonal Responses to Exercise in Patients With Fibromyalgia.
Conditions
Keywords
Fibromyalgia, Whole-Body vibration, Exercise, IGF-1
Brief summary
The purpose of this study was to investigate the acute and chronic effect of whole-body vibration exercise on serum insulin-like growth factor-1 levels in women with fibromyalgia (FM). It was hypothesized that women with FM would exhibit an increase in IGF-1 following both acute and chronic WBV. Twenty-four women with FM were randomized into two groups: Vibration Group (VG) and Control Group (CG). The VG underwent a protocol with WBV exercise twice a week for a total of six weeks, whereas the CG performed the same protocol without vibratory stimulus. Both groups continued with their usual pharmacological treatment. Serum IGF-1 levels were determined using Enzyme-Linked Immunosorbent Assay (ELISA). To test the effect of chronic WBV, serum IGF-1 measurements were taken at baseline and at weeks 1,3, and 6 of intervention. To test the effect of acute WBV, within week 1, serum IGF-1 measurements were taken before and immediately following a session of WBV.
Interventions
DEVICEVibratory platform, PowerPlate®, Badhoevendorp, Netherlands
Six exercises (static and dynamic tasks) while standing on a Whole-body vibration platform. The six exercises (30 seconds each) were repeated six times with a recovery of 3 minutes in between. The Whole-body vibration intensity was kept constant at 30 Hz of frequency and 2 mm of amplitude.
DEVICEPlacebo Whole-body vibration exercise
Six exercises (static and dynamic tasks) while standing on a Whole-body vibration platform. The six exercises (30 seconds each) were repeated six times with a recovery of 3 minutes in between. All exercises were performed without the influence of a vibratory stimulus.
Sponsors
Institut Nacional d'Educacio Fisica de Catalunya
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
35 Years to 69 Years
Healthy volunteers
No
Inclusion criteria
* Patients diagnosed of fibromyalgia according to the American College of Rheumatology criteria for at least three years.
Exclusion criteria
* Orthopedic limitation, or cardiovascular, pulmonary, or metabolic disease that would preclude exercise. * Participation in any other study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum IGF-1 levels | Baseline, Week 1, Week 3, Week 6 |
Countries
Spain
Outcome results
None listed