Whole Blood-plasma-oral Fluid Ratios of Psychoactive Drugs and Medicines

DRUID Sub-study: Substance Concentration Ratio/Impairment

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00650130

Enrollment

300

Registered

2008-04-01

Start date

2008-05-31

Completion date

2011-10-31

Last updated

2013-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Driving Under the Influence

Keywords

driving under the influence, psychoactive substances, oral fluid, whole blood, plasma, Ratio of psychoactive substances in whole blood-plasma-oral fluid, Prevalence of psychoactive substances in road traffic

Brief summary

The aim of this study is to get new information on the whole blood-plasma-oral fluid ratios of psychoactive drugs which are encountered in traffic. Samples are taken from drivers suspected of being under the influence of drugs or medicines. The samples are analysed with immunological methods and GC-MS. Observations from Police and a physician on impairment are combined with the results of the different bodily fluids. Observational evaluations and substance concentrations are compared.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* 18 years or older * driver of a motorised vehicle

Exclusion criteria

* 17 years or younger * not the driver of a motorised vehicle

Design outcomes

Primary

Measure	Time frame
ratio of psychoactive drugs/medicines in whole blood-plasma-saliva and correlation to symptoms of impairment	1 year

Secondary

Measure	Time frame
prevalence of psychoactive substances in the general driving population	three years

Countries

Finland

Outcome results