Predisposing Factors for Chronic Postherniotomy Pain

Prospective Study of Predisposing Factors for Chronic Postherniotomy Pain

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00649142

Enrollment

455

Registered

2008-04-01

Start date

2007-01-31

Completion date

2008-09-30

Last updated

2009-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Postherniotomy Pain

Keywords

Groin hernia, Chronic postsurgical pain, open mesh repair, laparoscopic mesh glue fixation, Sensory changes after groin hernia repair

Brief summary

Chronic pain affects pain in 5-8% of patients more than a year after groin hernia repair. However no prospective study has investigated potential predisposing factors for development of pain, including genetic, psychosocial and detailed neurophysiological assessment of surgical method. The current study will assess the above factors in a prospective study.

Interventions

PROCEDUREOpen sutured mesh repair

Open sutured mesh repair

PROCEDURELaparoscopic mesh glue fixation

Laparoscopic mesh glue fixation

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Adult (\>18 years) * Male * Primary unilateral groin hernia * Ability to use pain scales

Exclusion criteria

* Neurological disease * Diabetes with late stage complications

Design outcomes

Primary

Measure	Time frame
Frequency of chronic pain	6 months postoperatively

Secondary

Measure	Time frame
Changes in sensory function	6 months
Influence of genotype, preoperative pain, intraoperative findings, psycho-social factors	6 months

Countries

Denmark, Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026