Labor Pain
Conditions
Keywords
Epidural analgesia, Latent analgesia, Active analgesia, Labor delivery
Brief summary
Painless labor is an essential part in woman's health care. Labor analgesia in the active phrase is in popular use currently. However, parturients are still haunted by the labor delivery pain in the latent phrase up to 7-8 hours, especially for the nulliparas. Therefore, we hypothesized that labor analgesia in the latent phrase of the first delivery stage would provide superior health care for laboring women. In addition, such analgesia technique would not prolong the time of uterine dilation and labor delivering.
Interventions
PROCEDUREActive phrase epidural analgesia
Continuous epidural analgesia with sufentanil plus ropivacaine
PROCEDURELatent phrase epidural analgesia
Continuous epidural analgesia with sufentanil plus ropivacaine
Sponsors
Nanjing Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Nulliparas * Required labor analgesia * Chinese.
Exclusion criteria
* Allergic to opioids and/or local anesthetics * Failed to performing epidural catheterization * Organic dysfunction * Contraindications for epidural analgesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of Cesarean delivery | The time of the end of the labor |
Secondary
| Measure | Time frame |
|---|---|
| Time of labor | From the beginning of regular contraction of uterus to the end of the labor |
| Overall feeling of satisfaction of analgesia | From the beginning of regular contraction of uterus to the end of the labor |
| Side effects | From the beginning of regular contraction of uterus to the end of the labor |
| VAS pain intensity | From the intinition of analgesia to the cervical dilation >4cm |
| Instrumental delivery | The end of the time of the labor |
| Time of latent phrase | From the beginning of regular contraction of uterus to the diameter of cervix to 4cm |
| Neonatal Apgar scores | 1st min, 5th min, 10th min and 20th min |
| Umbilical gas measurement | After delivering of the fetus |
| Maternal oral temperature | From the initiation of analgesia to the end of the labor |
| Maternal corticosteroids | 1h before analgesia; 0h of the analgesia; 5min,10min,30min,45min,1h,2h,3h and hourly till the end of the labor |
| Oxytocin infusion rate | During the whole period of laboring |
Countries
China
Outcome results
None listed