Microbial Invasion During Parenteral Nutrition in Surgical Infants Receiving Glutamine

Microbial Invasion During Parenteral Nutrition in Surgical Infants Receiving Glutamine.

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00647036

Enrollment

Registered

2008-03-31

Start date

2009-07-31

Completion date

2012-05-31

Last updated

2022-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical Infants Requiring Total Parenteral Nutrition

Keywords

Parenteral nutrition, Infants, Dipeotiven, Microbial invasion

Brief summary

We hypothesise that the addition of glutamine supplementation to both parenteral nutrition and enteral feeds in surgical newborn infants leads to a reduction in bacterial invasion.

Interventions

DIETARY_SUPPLEMENTIsonitrogenous Vaminolact

Isonitrogenous Vaminolact

DRUGDipeptiven (L-glutamine- Lalanine)

0.6g/kg/day

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

OTHER

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

No minimum to 3 Months

Healthy volunteers

Inclusion criteria

* Infants who have undergone surgical procedures for congenital anomalies or * Intestinal inflammation who require total parenteral nutrition.

Exclusion criteria

Design outcomes

Primary

Measure	Time frame
Evidence of microbial invasion	5 days

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026