Asthma
Conditions
Keywords
asthma, adults, Symbicort, budesonide/formoterol, Advair Diskus, Ventolin
Brief summary
The purpose of this study is to compare the early onset of effect of Symbicort compared to Advair Diskus and Ventolin in adults with asthma
Interventions
Sponsors
AstraZeneca
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* At least 18 years of age * Diagnosis of asthma and baseline lung function test results as determined by the protocol * Required and received inhaled corticosteroids within timeframe and doses specified in the protocol
Exclusion criteria
* Severe asthma or asthma that is markedly effected by seasonal factors * Has required and received non-inhaled corticosteroids within the previous 4 weeks, has sensitivity to drugs specified in the protocol or requires treatment with beta-blockers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FEV1 3 minutes post dose | 4 assessments across 4 visits whilst on treatment (visits may be between 3 and 14 days apart) |
Secondary
| Measure | Time frame |
|---|---|
| 12 hour serial FEV1 | 4 assessments across 4 visits whilst on treatment (visits may be between 3 and 14 days apart) |
| Patients perception of effect | Patients perception of effect |
Outcome results
None listed