Psychological Effects of Bone Marrow Transplants in Children

Proposal for a Bone Marrow Transplant Pre, Post, and Long Term Psychological Evaluation Study.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00645931

Enrollment

Registered

2008-03-28

Start date

2004-06-30

Completion date

2009-12-31

Last updated

2023-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psychological

Keywords

Bone Marrow, Bone Marrow Transplant, Pediatric, Psychological Impact, Psychology

Brief summary

This study is designed to examine the psychological effects of bone marrow transplants on children and their families. The investigators hypothesis is that families who show signs of psychological distress before transplant will continue those signs post transplant. The investigators are examining cognitive placement, emotional placement and other psychological factors in both the child undergoing transplant and his or her parent.

Detailed description

Previous research on bone marrow transplants has conflicting results concerning the effects of maladjustment. The current research is conducted in consortium with DeVos Children's Hospital. Children receiving bone marrow transplants are assessed using the Child Behavior Check List (CBCL) and Cognitive based testing. Parents are assessed using the Parenting Stress Index (PSI). Children and parents are evaluated prior to transplant and then 50 days, 6 months, and one year post transplant. Descriptive statistics are currently being used to determine results.

Interventions

BEHAVIORALprotein and calorie controlled diet and self-hypnotic relaxation

daily

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Days to 18 Years

Healthy volunteers

Inclusion criteria

* bone marrow transplant eligible patients * 18 years and under * male and female

Exclusion criteria

* over the age of 18

Design outcomes

Primary

Measure	Time frame
The specific measure that will be used to determine the effect of the intervention(s). The description should included the time at which the measure will be taken. Examples: all cause mortality at one year; score on a depression rating scale at 6 weeks	1 year post transplant

Secondary

Measure	Time frame
Other measures that will be used to evaluate the intervention(s), and that are specified in the protocol. The description should include the time at which the measures will be taken. Ex. cardiovascular mortality at 6 mos.; functional status at 4 wks	1 year post transplant

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026