Dyslipidemia, Metabolic Syndrome, Obesity
Conditions
Keywords
Weight loss, Antiobesity, Metabolic syndrome, Leptin
Brief summary
The study investigated the use and efficacy of the seeds of African bush mango (Irvingia gabonensis)to control body weight, blood lipids and hormones in overweight and obese people.
Detailed description
To assess the effects of seeds of Irvingia gabonensis on body weight, fasting blood glucose, plasma total and LDL cholesterol in 102 overweight and obese participants. The study was a 10 week randomized, double blind, placebo controlled design. participants were randomly divided into 2 groups of 51 participants each. Group 1 was the placebo group, while Group 2 was the active group. Each group received 2 daily doses of 125 mg (before meals) of either placebo or Irvingia gabonensis. Weight as well as fasting blood was taken at baseline and at 4, 8 and 10 weeks. No major detary changes or exercises were suggested during the study period.
Interventions
DIETARY_SUPPLEMENTIGOB131
Comparison of 250 mg per day of Irvingia gabonensis to placebo
Sponsors
University of Yaounde
Gateway Health Alliance
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
19 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI\>26
Exclusion criteria
* Diabetics Pregnant and lactating Participating in any other weight reducing program Smokers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight change | 10 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Change in blood lipids and hormone levels | 10 weeks |
Countries
Cameroon
Outcome results
None listed