The Effect of Leucine on Body Composition and Muscle Characteristics in Elderly, Type 2 Diabetes Patients

The Influence of Leucine Supplementation on Body Composition and Muscle Characteristics in Elderly, Type 2 Diabetes Patients.

Status

Completed

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00643773

Enrollment

Registered

2008-03-26

Start date

2008-05-31

Completion date

2010-06-30

Last updated

2011-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes

Keywords

Elderly

Brief summary

The purpose of this study is to determine whether long term leucine supplementation has a positive effect on body composition and muscle characteristics in elderly, type 2 diabetes patients.

Interventions

DIETARY_SUPPLEMENTLeucine

capsules are 0.5g, subjects take 5 capsules with every main meal for 6 months In total this is 15 capsules per day

DIETARY_SUPPLEMENTWheat flour

Wheat flour

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

MALE

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* Clinical diagnosis of type 2 diabetes

Exclusion criteria

* Impaired renal or liver function * Cardiac disease * Subjects with metal implants * Hypertension * Diabetes complications * Exogenous insulin therapy

Design outcomes

Primary

Measure	Time frame
Body Composition	1, 3, and 6 months

Secondary

Measure	Time frame
Muscle characteristics	1, 3, and 6 months

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026