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A Comparison of Hemorrhagic and Ischemic Strokes Among Blacks and Whites

A Comparison of Hemorrhagic and Ischemic Strokes Among Blacks and Whites: A Population-Based Study in Cincinnati, Ohio

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00642213
Acronym
GCNKSS
Enrollment
1500
Registered
2008-03-24
Start date
1993-07-31
Completion date
2025-06-30
Last updated
2024-09-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemorrhage, Ischemic Stroke, TIA

Keywords

stroke, ischemic, TIA, hemorrhage, incidence, case-fatality, risk factors, genetic

Brief summary

Our primary goal is to study temporal trends in the incidence rate, causes, treatment, and outcome of stroke among a large biracial metropolitan population of 1,349,351, of whom 215,611 (15%) are black (2000 Census). Such data are critical for the planning, intervention, and evaluation of public health efforts to decrease the mortality and morbidity due to stroke in the United States. We have completed this goal for 1993-94, 1999, 2005, 2010 and 2015. We are in the process of collecting this data for 2020. In the 2020 study period we will also be ascertaining 3 year recurrence rates for all incident stroke events.

Detailed description

For calendar years 1993-94, 1999, 2005, 2010, 2015, and 2020 we will or have identified every hospitalized or autopsied stroke and transient ischemic attack (TIA) at all regional hospitals in our region. We will also estimate the number of non-hospitalized strokes and TIAs by screening for potential cases at more than 100 outpatient sites throughout five counties in Greater Cincinnati/Northern Kentucky. We plan to identify and abstract detailed information from the medical record for every potential case. These results will be compared with data from all stroke patients identified by similar methodology in all study periods. In addition, we have interviewed 1500 ischemic stroke patients and/or their families in the study periods 1999-2010 to obtain detailed information including demographic information, functional outcome and quality of life, access to and type of rehabilitation therapy, social support, caregiver availability and health status, access to post-hospital care, health insurance status, current health status, medications, prior risk factors, and knowledge about stroke signs and symptoms. We also obtained genetic material via a blood sample for most of this cohort.

Interventions

None listed

Sponsors

National Institute of Neurological Disorders and Stroke (NINDS)
CollaboratorNIH
University of Cincinnati
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* ischemic stroke * occurred in 1999/2005/2010 * \>18 years old * resides in 5 county region

Exclusion criteria

* \<18 years old * resides outside 5 county region * inability to consent or have legal proxy consent

Design outcomes

Primary

MeasureTime frameDescription
mRSdischarge or 30 daysmodified Rankin Scale

Secondary

MeasureTime frameDescription
mortality1 yearentire patient population checked for possible death record via NDI/CDC

Other

MeasureTime frameDescription
2020 Stroke population mRS3 month, 6 month, and 1 yearwe will collect 3 months, 6 months, and 1 year mRS outcomes on the 2020 stroke patients

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 15, 2026