Automated Chest Compression in Cardiac Arrest

Effect on Hemodynamics of Automated Band Chest Compression Device in Cardiac Arrest Resuscitation

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00641069

Enrollment

Registered

2008-03-21

Start date

2008-02-29

Completion date

2009-01-31

Last updated

2009-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Arrest

Keywords

Cardiac arrest, Cardiopulmonary resuscitation

Brief summary

To evaluate the effect of use of automated chest compression device on blood pressure in patients presenting with cardiac arrest. Higher systolic, diastolic and mean blood pressures are expected.

Detailed description

The protocol compares arterial pressures produced by an automated self-adjusting load-distributing band device (AutoPulse™ 100, Zoll®) with those of manual cardiopulmonary resuscitation in refractory out-of-hospital cardiac arrest. Each patient will receive first manual compressions and then automated resuscitation. Patients presenting with cardiac arrest are treated following standard advanced life support guidelines. They are intubated and ventilated, received epinephrine and defibrillation if appropriate. Manuel chest compressions are continued. An arterial catheter is placed to monitor hemodynamics continuously as we usually do in this case. Patients are included at this stage. Three blood pressure values (every 1 minutes) are recorded. Then, the automated band device is started up without any pause, following our procedure for refractory cardiac arrest. Three blood pressure values are recorded again, during automated cardiopulmonary resuscitation.

Interventions

DEVICEAutomated load-distributing band device

Blood pressure recording before and after starting up the automated band device

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age ≥ 18 * Refractory cardiac arrest

Exclusion criteria

* Defective invasive arterial blood pressure monitoring

Design outcomes

Primary

Measure	Time frame
Diastolic blood pressures produced by manual and then by automated chest compressions will be recorded for each patient	Instantaneously

Secondary

Measure	Time frame
Systolic blood pressures produced by manual and then by automated chest compressions will be recorded for each patient	Instantaneously
Mean blood pressures produced by manual and then by automated chest compressions will be recorded for each patient	Instantaneously

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026