Varicocele
Conditions
Keywords
Varicocele
Brief summary
In varicocele the venous pressure in the prostatic bed is increased .This may result in raised hydrostatic pressure which in turn may stimulate prostatic hypertrophy. Restoring normal venous drainage is expected to lower hydrostatic pressure followed by inhibition of prostatic growth and possibly leading regression in prostatic dimensions.
Detailed description
35 male patients, aged 45 years or older, with documented benign prostatic hypertrophy (BPH)and varicocele as visualized by ultrasound and/or termography examination will be enrolled. Each patient will undergo a full urologic examination to exclude possible malignancy as well as a thorough medical examination to establish eligibility for treatment. In all selected patients the varicocele will be obliterated by means of embolization of the spermatic veins. The patients will be followed every three months by abdominal ultrasound as well as by serial PSA for a period of 6-12 months.
Interventions
PROCEDURESclerotherapy
Super-selective retrograde venography and sclerotherapy of internal spermatic veins and associated venous bypasses and retro-peritoneal collateral
Sponsors
Maaynei Hayesha Medical Center
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
45 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Male * Age \> 45 \< 80 years * BPH * Bilateral varicocele.
Exclusion criteria
* Coagulation disturbance * CHF * Malignancy * Renal failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety performance of the procedure. Reduction of above 20% in prostatic calculated volume. | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of above 20% in nocturia | 1 year |
Countries
Israel
Outcome results
None listed