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UGIST: Ultrasound Guided Internal Jugular Short-Term Central Venous Catheters Tunneling

UGIST Pilot Trial: Ultrasound Guided Internal Jugular Short-Term Central Venous Catheters Tunneling. Does it Reduce the Technical Difficulty and Mechanical Complications?

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00639197
Acronym
UGIST
Enrollment
20
Registered
2008-03-20
Start date
2008-03-31
Completion date
Unknown
Last updated
2008-04-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacteremia, Infection

Keywords

Tunneling, Short term, central venous catheters, Ultrasound Guided, Internal jugular, Assess safety and improve technical difficulty

Brief summary

The purpose of the study is to determine if tunneling standard short-term central lines for a short distance under the skin, with the assistance of ultrasound imaging, reduces the risk of central line infections for catheters placed in the neck vein. Previous work has shown that these lines can be tunneled without ultrasound guidance. We wish to determine if the use of ultrasound makes the tunneling procedure safer and easier.

Detailed description

More than 250,000 vascular catheter-related bloodstream infections occur annually in the USA with a mortality ranging from 12% to 25% in critically ill patients. It is also widely accepted that the internal jugular site is associated with a higher risk of catheter related infection if compared with the subclavian site. Therefore, the benefit of catheter tunneling was best seen at the internal jugular site as described by J F Timsit in 1996 in his prospective randomized multicentre study where it significantly decreased the rate of catheter related sepsis from 11.4% to 3.4%. At the same time, tunneling catheters did not increase the rate of mechanical complications such as pneumothorax, hematoma, or arterial puncture, but it almost doubled the rate of technical difficulties, such as problems with advancing the catheter or multiple puncture sites, at that time it was a blind technique. Now, and with the introduction of the ultrasound guidance in our routine central line insertions, we would like to evaluate its benefit in reducing the technical difficulty and mechanical complications that used to be encountered while tunneling the short term central venous catheters at the internal jugular site.

Interventions

PROCEDURETo tunnel

Using the standard Seldinger technique and under the guidance of ultrasound, the catheter will pass through a 3-5cm subcutaneous tunnel before it is eventually secured to reside at the internal jugular vein.

PROCEDUREStandard (not to tunnel)

Using the standard Seldinger technique and under the guidance of ultrasound, the catheter is secured to reside at the internal jugular vein, without a subcutaneous tunnel.

Sponsors

Hamilton Health Sciences Corporation
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult ICU patients. * Likely to need the line for 48 hours. * Standard central venous catheter.

Exclusion criteria

* Mechanical impedance (e.g C-spine protection). * Absent Internal jugular vessel on U/S. * Previous line still in place. * Presence of overlying skin or tissue infection or mass. * Tricuspid valve vegetation. * Tumor extending to the right atrium. * Persistent coagulopathy. * Newly inserted Pacemaker leads. * Recent carotid endarterectomy on same side. * No ultrasound facility available. * Patients requiring special lines (e.g. Dialysis).

Design outcomes

Primary

MeasureTime frame
Reduction in Technical difficulty6-8 weeks for the whole 20 pts.

Secondary

MeasureTime frame
Signs of line related blood stream infection/bacteremia.6-8 weeks for all 20 pts.

Countries

Canada

Contacts

Primary ContactSalah A Taqi, MBChB
sataqi@hotmail.com905-521-2100
Backup ContactCorey Sawchuk, MD
ctw_sawchuk@yahoo.com905-527-4322

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026