Impact of Conservative Treatment by Custom-made Orthoses in Patients With Haemophilic Ankle Arthropathy

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00638001

Enrollment

Registered

2008-03-18

Start date

2008-03-31

Completion date

2012-03-31

Last updated

2014-07-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haemophilia A, Haemophilia B

Keywords

patients with haemophilia A moderate or severe, patients with haemophilia B moderate or severe

Brief summary

The purpose of this study intend to evaluate the effectiveness of functional orthoses (including custom-made insoles and shoes) for preventing and controlling repetitive haemarthrosis in patients suffering of haemophilic ankle arthropathy, as well as the orthoses' impact on foot health-related quality of life.

Interventions

DEVICEcustom-molded insoles and custom-molded shoes

* custom-made insoles in PELITE foam (hypoallergenic prosthesis grade foam) or leather top cover cork insoles for patients suffering of mild to moderate ankle arthropathy * custom-molded shoes in leather for patients suffering of end-stage ankle arthropathy

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

13 Years to 80 Years

Healthy volunteers

Inclusion criteria

* haemophilia A or B, aged more than 13 years

Exclusion criteria

* impossibility to walk on a treadmill * recent joint haemarthrosis or muscle haematoma

Design outcomes

Primary

Measure	Time frame
Gait analysis, foot pressure measurement, specific joint score	To, T1 (3months) and T2 (6months)

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026