Transient Elastography and Variceal Bleeding

Can Liver Stiffness Values Predict Early Rebleeding in Variceal Rupture

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00635687

Acronym

PROME

Enrollment

Registered

2008-03-14

Start date

2008-03-31

Completion date

2012-05-31

Last updated

2013-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bleeding

Keywords

variceal bleeding, transient elastography

Brief summary

Transient elastography is a new non-invasive rapid and reproducible method, allowing evaluating liver fibrosis by measurement of liver stiffness. The aim of our study is to evaluate if the liver stiffness can predict the recurrence of upper variceal bleeding in cirrhotic patients hospitalized for variceal rupture.

Interventions

DEVICEFibroscan

transient elastography measure - Liver stiffness

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Informed consent form signed * Social security affiliation * Variceal bleeding with hematemesis or melena within 24 hours of inclusion * Age \> 18 years * Scheduled to undergo endoscopy within 24 hours of hospital admission

Exclusion criteria

* Hepatocarcinoma * Upper Gastro Intestinal bleeding for other causes than variceal bleeding * Concomitant disease with a life expectancy of less than 45 days * Rebleeding within 24 hours after first endoscopy * Technical failure of transient elastography

Design outcomes

Primary

Measure	Time frame
Bleeding recurrence rate	J45 post first hemorrage

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026