Rheumatoid Arthritis
Conditions
Keywords
rheumatoid arthritis, hands, randomized controlled, low level laser
Brief summary
The purpose of the present study was to assess the effectiveness of low-level laser therapy on the reduction in pain and improvement in function in the hands of patients with rheumatoid arthritis
Detailed description
Rheumatoid arthritis (RA) is a chronic inflammatory disease of unknown etiology that basically compromises the joints in a generalized, symmetrical, additive and usually progressive manner. This clinical condition includes pain and altered functionality. Low-level laser therapy (LLLT) has been studied since the 1970s with regard to its therapeutic effects. The literature suggests that it offers analgesic as well as anti-inflammatory benefits. A number of studies carried out in the laboratory and on animals have shown that LLLT contributes toward the treatment of inflammatory joint disease. However, studies on humans with RA have yielded controversial results. A large part of the authors researched state that further randomized double-blind controlled studies should be carried out to prove the effectiveness of LLLT on RA. Thus, the aim of the present study was to assess the effectiveness of LLLT on the reduction in pain and improvement in function in the hands of patients with RA.
Interventions
OTHERphototherapy
The laser used was low-level Aluminum Gallium Arsenide (AlGaAs)diodo laser, at a wavelength of 785 nm (infrared), dose of 3 J/cm2, mean power of 70 mW, 3 sec. per point, laser beam of 0,06cm2, BIOSET brand - Indústria de Tecnologia Eletrônica Ltda -Rio Claro, Brazil.
OTHERphototherapy placebo
disconnected laser (same device - experimental group)
Sponsors
Federal University of São Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients with RA * inflammatory condition of at least two hand joints among the wrists, proximal interphalangeal (PIP) joint and metacarpophalangeal (MCP) joint * visual analogue scale (VAS) for pain between 3 and 8 cm during activities of daily living * and being of either gender
Exclusion criteria
* skin lesions at the application site * other illnesses affecting the hands; physiotherapy for the hands in the previous three months * joint injections in the previous three months * change in disease-modifying anti-rheumatic drugs in the previous three months * and change in corticosteroids in the previous month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain | 2 months |
Secondary
| Measure | Time frame |
|---|---|
| function | 2 months |
Countries
Brazil
Outcome results
None listed