Pentoxifylline and Endometriosis

Combined Laparoscopic Surgery and Pentoxifylline Therapy for Treatment of Endometriosis-Associated Infertility: A Preliminary Study

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00632697

Acronym

LETS1

Enrollment

104

Registered

2008-03-11

Start date

2001-10-31

Completion date

2006-12-31

Last updated

2008-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis-Associated Infertility

Keywords

endometriosis, immunomodulation, infertility, laparoscopic surgery, pentoxifylline

Brief summary

To prove efficacy of an immunomodulator called pentoxifylline in the treatment of endometriosis in infertile patients undergoing laparoscopy surgery

Interventions

DRUGpentoxifylline

800 mg daily for six months

DRUGplacebo

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Inclusion criteria

* Infertile patients having early endometriosis as the only factor of their infertility

Exclusion criteria

* Previous treatment for endometriosis or patients having pelvic disorders in addition to endometriosis

Design outcomes

Primary

Measure	Time frame
Pregnancy rate	6 months follow-up

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026