Breath Analysis by Ion Mobility Spectrometry

Detection of Clusters of Volatile Organic Compounds (VOC)in Patients With Different Lung Disorders by Ion Mobility Spectrometry. Different Clusters of VOC in the Diagnosis of Different Lung Disorders Using Ion Mobility Spectrometry

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00632307

Enrollment

1000

Registered

2008-03-10

Start date

2006-07-31

Completion date

2023-12-31

Last updated

2022-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Diseases

Keywords

lung tumor, pleural tumor, interstitial lung disease, airway infection, COPD, sleep apnea, ion mobility spectrometry, breath analysis

Brief summary

Recognition of disease specific clusters of volatile organic compounds in patients with different lung diseases, using breath analysis with ion mobility spectrometry. Lung diseases of interest are: * COPD * tumors * airway infection * interstitial lung disease * sleep apnea Hypothesis: Breath analysis with ion mobility spectrometry can differentiate pulmonary disorders.

Detailed description

Recruitment of patients with different lung diseases goes on. First sub-group analysis of patients with COPD,lung cancer and sarcoidosis is done in order to create a training set of VOC-clusters for further validation in a bigger population of patients.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Yes

Inclusion criteria

* Any patient * Ages 18-90 years old

Exclusion criteria

\- Patient who are not able to perform an exhalation manoever.

Design outcomes

Primary

Measure	Time frame
Identification of diseases specific VOCs	years

Secondary

Measure	Time frame
Change of disease specific VOCs under therapy	years

Countries

Germany

Contacts

Primary ContactMichael Westhoff, MD

michael.westhoff@lkhemer.de004923729082203

Backup ContactPatric Litterst, MD

pneumologie@lkhemer.de004923729082545

Outcome results