Study of the Effect of Lactisole on the Intestinal Glucose Uptake

Study on the Effect of Lactisole on the Intestinal Glucose Uptake

Status

Completed

Phases

Phase 1Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00631293

Enrollment

Registered

2008-03-07

Start date

2008-03-31

Completion date

2008-04-30

Last updated

2009-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Healthy volunteers

Brief summary

Study of the effect of lactisole on glucose uptake

Interventions

OTHERplacebo

administration of placebo followed by lactisole

DIETARY_SUPPLEMENTlactisole

administration of lactisole followed by placebo

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

MALE

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Male subject, between 18 and 50 years * General good health condition

Exclusion criteria

* Overweight (Body Mass Index ≥30) * Metabolic disorders * History of gastrointestinal disorders * Regular (daily) intake of medication * Smoking more than 10 cigarettes/day * History of drug abuse * Exhaustive (\> 3 units/day) alcohol consumption * Exhaustive (\> 5 units/day) caffeine consumption (coffee, tea, cola, or other caffeine based drinks) * Recent (in the last 14 days) donation of blood * Recent (in the last 2 days) donation of blood plasma * Participation in another trial within 4 weeks before the start of the study

Design outcomes

Primary

Measure	Time frame
Differences in glucose uptake rate in lactisole treated subjects versus placebo treated subjects during oral glucose tolerance test	5 weeks

Secondary

Measure	Time frame
Differences in blood insulin, glucagon, triglycerides, GIP and GLP-1 in lactisole treated subjects versus placebo treated subjects during oral glucose tolerance test, ECG	5 weeks

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026