Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain

Inclusion criteria

Inclusion: * Moderate or severe post-operative pain following surgical extraction of two or more third molars, at least one of which must be a partial or complete bony mandibular impaction * In general good health with no contraindications to the study medication or rescue medication (tramadol or acetaminophen + hydrocodone) * Use of only short-acting local anesthetics with or without vasocontrictor and/or nitrous oxide Exclusion: * Presence of a serious medical condition (e.g., poorly controlled hypertension, diabetes, or hyper-/hypo-thyroidism; significantly impaired renal, cardiac, or hepatic function) * Acute localized dental alveolar infection at the time of surgery that could confound the post-surgical evaluation * Females who are pregnant, lactating, of child-bearing potential, or post-menopausal for less than 2 years and not using a medically-approved method of contraception