Breast Abnormalities
Conditions
Keywords
MR scanning
Brief summary
Preliminary imaging study to test for future use of this MRI-imaging for evaluating anti-angiogenesis treatment.
Detailed description
The purpose of this study is to develop and evaluate new MR imaging techniques and protocols for non-invasive monitoring of anti-angiogenesis treatment of breast cancer. This feasibility study is a preliminary imaging study to test this imaging protocol on subjects already undergoing MR for clinical purposes. The specific objective of this research study is to develop and validate both MRI and functional MRI data acquisition methods, task paradigms, and post-processing techniques to ensure reliability of results. The information derived from this research is intended to be applied to a future study of subjects undergoing experimental anti-angiogenesis drug therapy.
Interventions
DEVICEMRI
15-20 minutes MR imaging
Sponsors
Indiana University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Females * Age 18 years or greater * Undergoing breast MRI exam
Exclusion criteria
* Pregnancy * Contraindication for MRI on standard screening checklist for clinically indicated examinations (i.e. metal devices/implants; history of claustrophobia) * History/presence of any of the following to the breast: injury; breast implant; surgical or interventional procedure; clinically significant abnormality
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To provide preliminary data for a larger study that this type of imaging can be used to monitor the effectiveness of anti-angiogenic therapy. | After analysis of images |
Countries
United States
Outcome results
None listed