Diagnostic Value of Procalcitonin in Patients With Acute Appendicitis

A Prospective Study Investigating the Diagnostic Value of Procalcitonin in Patients With Acute Appendicitis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00630071

Enrollment

103

Registered

2008-03-06

Start date

2008-02-29

Completion date

2008-08-31

Last updated

2012-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Appendicitis

Keywords

Diagnostic Appendicitis, Procalcitonin

Brief summary

The values of laboratory examinations which are useful for the diagnoses of acute appendicitis are white blood cell count (WBC), C-reactive protein (CRP) and erythrocyte blood sedimentation rate (ESR). Another laboratory value which has recently received considerable attention for the early diagnosis of bacterial infection and sepsis is pro-calcitonin (PCT). In recent studies it has been clearly shown that PCT is one of the most important biochemical indicators which closely correlates with the severity of inflammatory host response to microbial infections. Aim of this open, prospective study is therefore to investigate if PCT has an accurate diagnostic value for the diagnosis of acute appendicitis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

14 Years to No maximum

Healthy volunteers

Inclusion criteria

* Clinical diagnosis of appendicitis

Exclusion criteria

* Antibiotic therapy * Infection at other body sites * Age \< 14 years * Appendectomy in the medical history

Countries

Germany

Outcome results