Coronary Artery Disease, Diabetes, Glucose Tolerance, Hyperlipidemia, Metabolic Syndrome
Conditions
Brief summary
The purpose of this study is to prospectivly analyze the correlation of triglyceride tolerance and glucose tolerance with cardiovascular morbidity and mortality in patients with stable coronary artery disease within 18 months and to determine, whether measurement of triglyceride tolerance can discriminate patients at risk for cardiovascular events.
Interventions
None listed
Sponsors
Universität des Saarlandes
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Stable CAD
Exclusion criteria
* Acute Coronary Syndrom * Relevant Arrhythmias * Severe valvular heart disease * Decompensated heart failure * Severe inflammtory disease (infectious, rheumatoid) * Metabolic diseases (e.g. thyroid) * Inability to swallow * Liver or kidney failure * Lactose intolerance * Fat intolerance (e.g. chronic pancreatitis, gall stones) * Malignant Disease * Psychiatric Diseases (including alcohol / drug abuse) * Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Parameters of triglyceride tolerance and glucose tolerance in correlation to cardiovascular events, cardiovascular mortality, total mortality. | 48 months after inclusion. |
Secondary
| Measure | Time frame |
|---|---|
| Waist-to-Hip ratio, nutrition protocol, physical activity, non-invasive endothelial function, body fat composition, other biomarkers of lipid and glucose metabolism. | Directly after inclusion. |
Countries
Germany
Outcome results
None listed