Pain
Conditions
Keywords
botulinum toxin a, botox, Decreasing botox injection pain, injections
Brief summary
This single blinded randomized pilot study was performed on 21 Caucasian females to determine if injections through follicular openings were less painful than traditional injections for cosmetic botulinum toxin type A injections.
Detailed description
Objective: To investigate whether injection of botulinum toxin type A is less painful if performed through follicular openings versus traditional non-specific approach. Design: Prospective, randomized, single-blinded study. Setting: Academic dermatology department. Patients: A volunteer sample of twenty female patients aged 25-55 who had no prior history of botulinum toxin injection. Intervention: Each patient received six randomized injections of botulinum toxin type A (Botox® Allergan). Two injections into the procerus muscle and two into each corrugator muscle. Three of the injections were performed through follicular openings and three were performed traditionally. Main Outcome Measure: Patient discomfort on a 1-10 scale and direct comparison between the two injection techniques.
Interventions
DRUGbotulinum type a
12 Units total were injected into 6 sites in the glabellar complex to determine if injecting through the follicle versus a traditional approach would decrease patient discomfort
Sponsors
Henry Ford Health System
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
25 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Female * No prior history of botulinum toxin * Age 25-55
Exclusion criteria
* Male * Prior history of botulinum toxin * Neuromuscular disorders * Aminoglycoside therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease pain on injection for treatment intervention assessed on a 10 point scale | At time of intervention |
Countries
United States
Outcome results
None listed