Trial of Myopia Prevention Using +3D Lenses

A Randomised, Controlled Trial of Prevention of Juvenile-Onset Myopia in Chinese Children

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00627874

Acronym

PLS

Enrollment

1200

Registered

2008-03-04

Start date

2010-04-30

Completion date

2012-04-30

Last updated

2009-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia

Brief summary

The purpose of this study is to assess whether a short-term imposed myopic defocus is effective in preventing the development and progression of juvenile-onset myopia in Chinese children.

Detailed description

1. To determine if +3D lenses wearing for half an hour everyday prevents the development and progression of myopia in school children. 2. To identify ocular parameters and risk factors at baseline associated with development and progression of myopia.

Interventions

DEVICE+3D Lenses

wear +3D glasses for 30 minutes per day and engage in activities which require vision at more than 1m

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* All children in the selected class are enrolled

Exclusion criteria

* Hyperopia \> +2.0 D * High myopia \> -6.0 D * Astigmatism\> 1.5 D * Anisometropia \> 1.5 D * Strabismus and amblyopia * Any ocular, systemic, or neurodevelopmental conditions that could influence refractive development * Chronic medication use that might affect myopia progression or visual acuity * Already receiving other treatment for progressing myopia

Design outcomes

Primary

Measure	Time frame
Axial Length of eyes	Annual

Secondary

Measure	Time frame
Autorefraction	Annual

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026