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Selective Neurectomy and Mesh Removal for Chronic Postherniotomy Pain

The Effect of Selective Neurectomy and Mesh Removal on Chronic Postherniotomy Pain

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00627289
Enrollment
21
Registered
2008-03-03
Start date
2008-02-29
Completion date
2008-12-31
Last updated
2014-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Keywords

Chronic pain, groin hernia, neuropathic pain, chronic postoperative pain, Postherniotomy pain, Neuroplastic changes

Brief summary

Chronic postherniotomy pain affects every day activities in 5-8% of patients. However, no established treatment for this pain syndrome exists and previous reports on the effect of surgical intervention suffer from methodological problems. The neurophysiological characteristics suggest that pain arises from deeper neuronal structures injured during surgery or by ongoing inflammation from the mesh. This study investigates the effect of removing inserted mesh and compressed nerves on pain related daily impairment of activities assessed by the validated AAS questionnaire before and 6 months after surgery

Interventions

None listed

Sponsors

Rigshospitalet, Denmark
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult ( more than 18 years old) patients with chronic pain after groin hernia surgery, and pain related impairment of everyday function. The pain should have occurred after previous open surgery. * The patient should be able to locate to a specific area with maximum pain. Patients should be able to understand and use pain scales, and the AAS-scale.

Exclusion criteria

* All that contradicts the above

Design outcomes

Primary

MeasureTime frame
changes in AAS scores before and six months after operation6 months

Secondary

MeasureTime frame
changes in sensory function assessed by quantitative sensory testing6 months

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026