Labor Analgesia With Ropivacaine and Clonidine

Labor Analgesia With Ropivacaine Added to Clonidine. A Randomized Clinical Trial

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00626977

Acronym

Enrollment

Registered

2008-02-29

Start date

2000-05-31

Completion date

2001-12-31

Last updated

2015-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor Pain

Keywords

Analgesia, Obstetrical, Anesthesia, Epidural, Newborn, Anesthetics, local, Clonidine, Pregnant women, Infant, newborn

Brief summary

The aim of the present study was to examine, for pain relief during labor, the efficacy of two pharmacological approaches - the 0.125% ropivacaine alone and the 0.0625% ropivacaine added to 75 ug clonidine, both by epidural administration. The effect of the drugs on mother and newborn was also determined.

Interventions

DRUGropivacaine

15 ml of ropivacaine 0.125% peridural once

DRUGropivacaine and clonidine

15 ml of ropivacaine 0.0625% plus 75 mcg clonidine

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Singleton healthy * Full-term pregnancy * American Society of Anesthesiologists physical status I or II

Exclusion criteria

* Patients who had received opioids * History of hypersensitivity to local anesthetic or to clonidine * Fetus showed signs of possible intrauterine suffering * Fetus showed signs of possible neurological deficit

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026