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Gene Polymorphisms in Tacrolimus Drug Interactions

Gene Polymorphisms in Tacrolimus Drug Interactions in Renal Transplant Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00620841
Acronym
DDI-TAC
Enrollment
40
Registered
2008-02-22
Start date
2007-05-31
Completion date
2008-01-31
Last updated
2008-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Transplantation

Keywords

Tacrolimus, Renal Transplantation, genetic polymorphisms, Drug drug interactions

Brief summary

A retrospective analysis of the influence of gene polymorphisms on drug interactions between calcineurin-inhibitors and concomitant drugs in renal transplant patients.

Interventions

OTHERgenotyping

Restriction fragment lenght polymorphisms

Sponsors

Fund for Scientific Research, Flanders, Belgium
CollaboratorOTHER
KU Leuven
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* Treatment with calcineurin-inhibitor * Renal transplantation

Exclusion criteria

* Drug, alcohol addiction

Design outcomes

Primary

MeasureTime frame
Tacrolimus exposure parametersweeks

Secondary

MeasureTime frame
Tacrolimus daily dosingweeks

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026