Polyphenols and Endothelial Function

Polyphenols Rich Fruit Juice Effects on Endothelial Function and Exercise Capacity

Status

Terminated

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00619749

Enrollment

Registered

2008-02-21

Start date

2008-03-31

Completion date

2012-03-31

Last updated

2016-07-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sedentary Subjects

Brief summary

To determine whether fruit juice rich in polyphenols might increase exercise capacity and memory in healthy sedentary subjects.Both parameters might be improved because of the anti-oxidant effects of polyphenols.

Interventions

DIETARY_SUPPLEMENTjuice rich in polyphenols

juice during 2 weeks

DIETARY_SUPPLEMENTjuice poor in polyphenols

juice during 2 weeks

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

30 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* sedentary

Exclusion criteria

* diabetes

Design outcomes

Primary

Measure	Time frame
Flow-mediated dilatation	2 years

Secondary

Measure	Time frame
Exercise, capacity memory	2 years

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026