Pulmonary Arterial Hypertension in Systemic Sclerosis

Stress Echocardiography in the Early Identification of Pulmonary Arterial Hypertension in Systemic Sclerosis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00617487

Enrollment

200

Registered

2008-02-18

Start date

2007-12-31

Completion date

2020-01-31

Last updated

2018-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Arterial Hypertension, Systemic Sclerosis

Brief summary

The purpose of this study is to evaluate the role of stress echocardiography, compared to standard echocardiography in the early identification of pulmonary arterial hypertension in systemic sclerosis. To evaluate the role of BNP in this setting.To analyze data recorded with respect to the parameters commonly used for SSc evaluation (eg thorax HRCT, pulmonary function tests + DLCO, nailfold capillaroscopy, etc); these parameters are available starting for 1999.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Patients with systemic sclerosis according to LeRoy criteria

Exclusion criteria

* Pregnancy * Significant valvular disease * Low left ventricular function upon echocardiography (ejection fraction\<55%) * History of atrial fibrillation, myocardial infarction, pulmonary thromboembolisms, neoplasia or severe hepatic disease.

Countries

Italy

Outcome results