Perioperative Temperature Management

Perioperative Temperature Management: A Big Small Problem

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00617136

Acronym

HOT

Enrollment

Registered

2008-02-15

Start date

2008-04-30

Completion date

2012-01-31

Last updated

2014-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypothermia

Keywords

Surgery, Anesthesia, Hypothermia, Temperature, Perioperative, Temperature Management

Brief summary

The investigators aim to investigate the effects of prewarming of patients undergoing elective orthopedic surgery on intraoperative temperature control and blood loss and postoperative patient discomfort and glucose and insulin levels.

Detailed description

Hypothermia, defined as a core temperature below 36 degrees celsius, is commonly seen in patients undergoing surgery. Intraoperative hypothermia is related to postoperative patient discomfort, impaired wound healing, increased blood loss, anxiety and disturbances in glucose and insulin levels. Prewarming of patients prior to surgery may result in maintenance of intraoperative temperature and reduce postoperative complications. We therefore aim to investigate the effects of prewarming of patients undergoing elective orthopedic surgery on intraoperative temperature control and blood loss and postoperative patient discomfort and glucose and insulin levels. Objective of the study: Does preoperative heating of patients undergoing elective orthopedic surgery reduce the incidence of intraoperative hypothermia and postoperative comfort and modulate postoperative glucose and insulin blood levels? Study design: Multi-center, prospective, randomized clinical trial. Study population: Patients undergoing an elective orthopedic hip- or knee replacement

Interventions

DEVICEIntraoperative warming (Bair Hugger)

Intraoperative warming

DEVICEPre- and intraoperative warming (HotDog)

Pre- and intraoperative warming by HotDog

DEVICEIntraoperative warming (HotDog)

Intraoperative warming

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* Patients undergoing an elective orthopedic knee- or hip replacement * Participation based on informed consent * \> 18 years old and \< 85 years old

Exclusion criteria

* BMI 18.5 \> x \< 40 * Pregnancy * Non elective trauma patients * Infectious or febrile patients (\> 37.5oC) * Diabetes Mellitus * Combined surgery * Anemia (Hb \< 4.0 mmol/l)

Design outcomes

Primary

Measure	Time frame
Incidence of perioperative hypothermia	During surgery (1 hour after start warming)

Secondary

Measure	Time frame
Perioperative blood loss	During surgery
Patient discomfort as defined by pain, nausea and vomiting, shivering and thermal discomfort	During surgery
Postoperative glucose and insulin levels	1 hour after surgery

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026