Interactive Psychopharmacologic Effects of Alcohol and Nicotine in Humans

Status

Completed

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00616746

Enrollment

Registered

2008-02-15

Start date

2007-01-31

Completion date

2010-06-30

Last updated

2014-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol Consumption, Tobacco Use

Keywords

Alcohol, nicotine

Brief summary

The purpose of this study is to characterize the interactive effects of acute intravenous (IV) alcohol and nicotine administration in male and female smokers and nonsmokers who use alcohol.

Interventions

DRUGNicotine

1.0 microg/kg/min IV x 10 minutes

DRUGEthanol

Study design

Allocation

Intervention model

SINGLE_GROUP

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

21 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Male or Female, 21 to 50 years old.

Exclusion criteria

* Alcohol or Nicotine Naive

Design outcomes

Primary

Measure	Time frame
Behavioral and Cognitive Measures	Baseline and Test Day

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026