Analysis of Microalbuminuria and Markers of Inflammation and Oxidative Stress in Adolescents of Different Ethnic Backgrounds

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00616707

Acronym

Enrollment

Registered

2008-02-15

Start date

2006-08-31

Completion date

2009-10-31

Last updated

2017-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammation

Keywords

Inflammation, Oxidative Stress, Microalbuminuria

Brief summary

The purpose of this study is to determine if there are signs of inflammation in one's blood and urine and to find out if one's body size or ethnicity has an effect on these substances.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

12 Years to 18 Years

Healthy volunteers

Inclusion criteria

* Adolescents between 12 to 18 years old * Hispanic, African American or Caucasian ethnicity * Have a Body Mass Index (BMI) between the 5th and 85th percentile or greater than the 95th percentile * Must currently be attending a UC Davis Pediatric clinic

Exclusion criteria

* Chronic liver or kidney disease, known Diabetes or other chronic illnesses (such as Sickle Cell Disease or Cystic Fibrosis) * Subjects can NOT be acutely febrile, smoke, chronically use prescription medications or oral contraceptive pills.

Design outcomes

Primary

Measure	Time frame
To compare plasma levels of inflammatory markers and urinary biomarkers of oxidative stress in adolescents of Hispanic, African-American and Caucasian ethnicity	at the end of study

Secondary

Measure	Time frame
To determine if there is an independent correlation between these markers and urinary microalbumin excretion	at the end of study

Countries

United States

Outcome results