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The Effect of Long-Chain Polyunsaturated Fatty Acids on Cognitive Performance and Mood

The Effect of Long-Chain Polyunsaturated Fatty Acids on Cognitive Performance and Mood of Healthy Young Adults

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00615277
Enrollment
82
Registered
2008-02-14
Start date
2006-10-31
Completion date
Unknown
Last updated
2008-02-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Young adults, Long-chain polyunsaturated fatty acids, Cognitive function, Mood, Supply with omega-3 fatty acids

Brief summary

The study investigates whether dietary intake of omega-3 long-chain polyunsaturated fatty acids affects learning and mood of healthy young adults.

Detailed description

The long-chain polyunsaturated fatty acids (LCPUFA) EPA (eicosapentaenoic acid), DHA (docosahexaenoic acid) of the omega-3 series and AA (arachidonic acid) of the omega-6 series are building blocks of all cell membranes and are found in high concentrations in retina and brain. Food sources of LA and ALA are vegetable oils, nuts and seeds. Since low conversion rates from ALA to DHA are a characteristic of human metabolism, adequate dietary provision with the long-chained omega-3 molecules depends primarily on individual eating habits. While AA is abundant in meat and dairy products, EPA and DHA are found in noteworthy concentrations only in certain species of fatty fish, such as salmon or mackerel. The study investigates whether participants receiving an omega-3 supplement over a period of 4 month, perform better on a series of cognitive tests, than the participants allocated to the placebo group.

Interventions

DIETARY_SUPPLEMENTOmega-3 fatty acids

600 mg EPA 120mg DHA daily, 16 weeks

Sponsors

Philipps University Marburg
CollaboratorOTHER
Cognitive Drug Research Ltd
CollaboratorUNKNOWN
University of Ulm
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
16 Years to 24 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy young adults

Exclusion criteria

* Coagulation disorder

Design outcomes

Primary

MeasureTime frame
CognitionBefore intervention and after 16 weeks of intervention

Secondary

MeasureTime frame
MoodBefore intervention and after 16 weeks of intervention

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026