Organization in Acute Atrial Fibrillation Post Open Heart Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00614107

Acronym

A-Fib

Enrollment

Registered

2008-02-13

Start date

2008-01-31

Completion date

2009-01-31

Last updated

2021-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Keywords

Atrial Fibrillation post open heart surgery

Brief summary

A form of irregular heart rate called, Atrial Fibrillation (AF) is a major clinical problem. It afflicts about 2 million Americans and is the single largest heart related cause of stroke. However, despite 120 years of speculation and research, the mechanisms that cause AF are poorly understood. Acute AF is also the most common irregular heart rate after open-heart surgery in patients. This is seen in as many as 30% of such patients and often results in a longer hospital stay. In this study we would like to study the pattern of atrial fibrosis (scar tissue in the heart) and an associated blood marker (a protein called pro-collagen-1) in those patients concurrently having open heart surgery.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 79 Years

Healthy volunteers

Inclusion criteria

1. 18 years of age, Male or Female 2. Able to provide consent 3. Cardiac surgery, CABG of Valve replacement or repair.

Exclusion criteria

1. If AF terminates within 1 hour of initiation. 2. If the patient undergoes electrical cardioversion and/or receives digitalis within the first hour of inclusion. 3. If the patients and/or their family or the primary caregiver choose to be excluded from the study anytime, even after the initial 24-hour period. 4. If the patient expires within 1 hour of inclusion into the study. -

Countries

United States

Outcome results